I think it would depend on what forces are gonna ultimately be placed on the wall when it’s done. If the brick and mortar pattern is very disorganized, that might lead to certain spots where stresses may concentrate in one place vs another. This would then mean the wall has certain spots where its more prone to failure, compared to a wall with a regular, even distribution of brick and mortar.

It’s kinda like why we heat treat some metals. To alter the grain structure of them to give us certain properties.