One account that can be correlated to place/city, willing to discuss local news and issues.

One account that can be correlated to family status, willing to mention details about relationships.

One account that can be correlated to career, willing to mention details about educational background, industry news, the job market, the workplace, etc.

One account that can be correlated to each distinct hobby or interest. Some interests can correlate among themselves (like an all sports account that discusses multiple sports) and are safe to discuss on a single account. Like my current account that is tech oriented, including some stuff about games or Linux or networking or even the tech industry. But keep the different interests on separate accounts.

Then different accounts for topics that you consider controversial or private.

And, preferably, spread all those accounts across multiple instances so that instance admins can’t link accounts from metadata (client, OS, IP address, email verification), use completely unique usernames, and avoid unique markers like esoteric phrases, unique autocorrect errors, etc.

Even if an adversary can link two accounts, they probably can’t link all of them.