Looking at the study, ‘female’, or ‘feminisation’/‘feminization’ isn’t used once. But ‘oestrogen’ appears a lot.
I guess some of these materials interfere with hormone activity and they call that feminisation? Still puzzled.
Bisphenols: Mostly used in the manufacturing of polycarbonate plastics and epoxy resins, bisphenols
are endocrine disruptors that mimic oestrogen , potentially leading to metabolic disorders, reproduc-
tive issues, and increased cancer risk even at trace concentrations (Maffini et al., 2006; Rochester &
Bolden, 2015)
PhP (Triphenyl phosphate): The most prevalent OPFR in our samples, TPhP is a confirmed endocrine
disruptor (Hu et al., 2023; Li et al., 2025). It interferes with oestrogen and thyroid hormone axes (Ji et al.,
and is linked to obesity and metabolic changes (Wang et al., 2019)
BPA (Bisphenol A): Binds to oestrogen receptors and alters gene expression and hormone activity (Alon-
so-Magdalena et al., 2012). BPA has been detected in amniotic fluid, placental tissue, and umbilical cord
blood, indicating transplacental transfer. Studies have confirmed that BPA can migrate from synthetic
materials into artificial sweat (Wang et al., 2019), and dermal absorption is well established (Toner et
al., 2018). These findings led to the EU ban of BPA in thermal receipt paper in 2020, although it has been
widely substituted with BPS (ECHA, 2020)
BPAF (Bisphenol AF): Demonstrates stronger oestrogenic activity than BPA and is increasingly used in
thermal paper and plastic applications (Moreman et al., 2017)
RDP (Resorcinol bis(diphenyl phosphate)): Used as a substitute to TPhP, RDP is an emerging neurotox-
in and acts as an endocrine disruptor that interferes with thyroid and oestrogen pathways. It has been
linked to metabolic imbalances in animal studies (Xie et al., 2023). Scientists report stronger oestrogen-
ic effects than TPhP and RDP´s exposure showing metabolic disorders in rats and their offspring (Liu et
al., 2023).
I’m also puzzled by this choice of words.
Looking at the study, ‘female’, or ‘feminisation’/‘feminization’ isn’t used once. But ‘oestrogen’ appears a lot. I guess some of these materials interfere with hormone activity and they call that feminisation? Still puzzled.